31 research outputs found

    An adaptive multi-agent system for self-organizing continuous optimization

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    Cette thèse présente une nouvelle approche pour la distribution de processus d'optimisation continue dans un réseau d'agents coopératifs. Dans le but de résoudre de tels problèmes, le domaine de l'optimisation multidisciplinaire a été proposé. Les méthodes d'optimisation multidisciplinaire proposent de distribuer le processus d'optimisation, généralement en reformulant le problème original d'une manière qui réduit les interconnexions entre les disciplines. Cependant, ces méthodes présentent des désavantages en ce qui concerne la difficulté de les appliquer correctement, ainsi que leur manque de flexibilité. En se basant sur la théorie des AMAS (Adaptive Multi-Agent Systems), nous proposent une représentation générique à base d'agents des problèmes d'optimisation continue. A partir de cette représentation, nous proposons un comportement nominal pour les agents afin d'exécuter le processus d'optimisation. Nous identifions ensuite certaines configurations spécifiques qui pourraient perturber le processus, et présentons un ensemble de comportements coopératifs pour les agents afin d'identifier et de résoudre ces configurations problématiques. Enfin, nous utilisons les mécanismes de coopération que nous avons introduit comme base à des patterns de résolution coopérative de problèmes. Ces patterns sont des recommandations de haut niveau pour identifier et résoudre des configurations potentiellement problématiques qui peuvent survenir au sein de systèmes de résolution collective de problèmes. Ils fournissent chacun un mécanisme de résolution coopérative pour les agents, en utilisant des indicateurs abstraits qui doivent être instanciés pour le problème en cours.In an effort to tackle such complex problems, the field of multidisciplinary optimization methods was proposed. Multidisciplinary optimization methods propose to distribute the optimization process, often by reformulating the original problem is a way that reduce the interconnections between the disciplines. However these methods present several drawbacks regarding the difficulty to correctly apply them, as well as their lack of flexibility. Based on the AMAS (Adaptive Multi-Agent Systems) theory, we propose a general agent-based representation of continuous optimization problems. From this representation we propose a nominal behavior for the agents in order to do the optimization process. We then identify some specific configurations which would disturb this nominal optimization process, and present a set of cooperative behaviors for the agents to identify and solve these problematic configurations. At last, we use the cooperation mechanisms we introduced as the basis for more general Collective Problem Solving Patterns. These patterns are high-level guideline to identify and solve potential problematic configurations which can arise in distributed problem solving systems. They provide a specific cooperative mechanism for the agents, using abstract indicators that are to be instantiated on the problem at hand

    Agent-Based Natural Domain Modeling for Cooperative Continuous Optimization

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    International audienceWhile multi-agent systems have been successfully applied to combinatorial optimization, very few works concern their applicability to continuous optimization problems. In this article we propose a framework for modeling a continuous optimization problems as multi-agent system,which we call NDMO, by representing the problem as an agent graph, and complemented with optimization solving behaviors. Some of the results we obtained with our implementation on several continuous optimization problems are presented

    A Natural Formalism and a MultiAgent Algorithm for Integrative Multidisciplinary Design Optimization

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    International audienceMultiDisciplinary Optimization (MDO) problems represent one of the hardest and broadest domains of continuous optimization. By involving both the models and criteria of different disciplines, MDO problems are often too complex to be tackled by classical optimization methods. We propose an approach which takes into account this complexity using a new representation (NDMO - Natural Domain Modeling for Optimization) and a self-adaptive multi-agent algorithm. Our method agentifies the different elements of the problem (such as the variables, the models, the objectives). Each agent is in charge of a small part of the problem and cooperates with others to find equilibrium on conflicting values. Despite the fact that no agent of the system has a complete view of the entire problem, the mechanisms we provide allow the emergence of a coherent solution. Evaluations on several academic and industrial test cases are provided

    Integration and evaluation of a near-infrared camera utilizing a HgCdTe NICMOS3 array for the Mt. Palomar 200-inch Observatory

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    In this paper we describe the main subsystems that constitute the Mt. Palomar Prime Focus InfraRed Camera (PFIRCAM), together with some of the characterization data obtained for the focal plane array. This camera is currently a facility instrument at the 200-inch Mt. Palomar Observatory. It helps to satisfy the observational needs of astronomers in the spectral range of 1 micrometers to 2.5 micrometers by utilizing a HgCdTe NICMOS3 array. The camera has a plate scale of 0.54 arcsec/pixel for an overall FOV of 138 X 138 arcsec

    Uncertainty propagation in multi-agent systems for multidisciplinary optimization problems

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    International audienceBecause of uncertainties on models and variables, deterministic multidisciplinary optimization may achieve under-sizing (without design margins) or over-sizing (with arbitrary design margins). Thus, it is necessary to implement multidisciplinary optimization methods that take into account the uncertainties in order to design systems that are both robust and reliable. Probabilistic methods such as reliability-based design optimization (RBDO) or robust design methods, provide designers with powerful decision-making tools but may involve very time-consuming calculations. New optimization approaches have been developed to deal with such complex problems. Auto-adaptive Multi-Agent Systems (AMAS) is a new approach developed recently, allowing to take into account the various aspects of a multidisciplinary optimization problem (multi-level, computation burden etc.). This approach was suggested for solving complex deterministic optimization problem. Now, the question of the integration of uncertainties in this multi-agent based optimization arises. The aim of this paper is to propose a new methodology for integrating the treatment of uncertainties in an adaptive multi-agent system for sequential optimization. The developed method employs a single loop process in which cycles of deterministic optimization alternate with evaluations of the system reliability. For each cycle, the optimization and the reliability analysis are decoupled from each other. The reliability analysis is carried out at agent level and only after the resolution of the deterministic optimization, to verify the feasibility of the constraints under uncertainties. Following the probabilistic study, the constraints violated (with low reliability) are shifted to the area of feasibility by integrating adaptive safety coeficients whose calculations are based on the agent-level reliability information. The method developed is applied to a conceptual aircraft design problem

    A novel approach to MDO using an adaptive multi-agent system

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    International audienceMultiDisciplinary Optimization (MDO) problems represent one of the hardest and broadest domains of continuous optimization, often too complex to be tackled by classical optimization methods. We propose an original approach for taking into account this complexity using a self-adaptive multi-agent system where each elements of the problem become an agent in charge of a small part of the problem

    Integration and evaluation of a near-infrared camera utilizing a HgCdTe NICMOS3 array for the Mt. Palomar 200-inch Observatory

    Get PDF
    In this paper we describe the main subsystems that constitute the Mt. Palomar Prime Focus InfraRed Camera (PFIRCAM), together with some of the characterization data obtained for the focal plane array. This camera is currently a facility instrument at the 200-inch Mt. Palomar Observatory. It helps to satisfy the observational needs of astronomers in the spectral range of 1 micrometers to 2.5 micrometers by utilizing a HgCdTe NICMOS3 array. The camera has a plate scale of 0.54 arcsec/pixel for an overall FOV of 138 X 138 arcsec

    Canagliflozin and renal outcomes in type 2 diabetes and nephropathy

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    BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years

    Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy

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    BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to 300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m 2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years

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